Dr Rajiv Desai
An Educational Blog
What Causes Cancer
What Causes Cancer: _ Figure above shows squamous cell carcinoma of the left anterior floor of mouth. _ Section-1 Prologue: International Cancer Institute has defined Cancer as a term used for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer is the second leading cause of death worldwide. Globally annually, there were an estimated 20 million new cases of cancer and 10 million deaths from cancer or nearly one in six deaths. The cancer burden will increase by approximately 60% over the next two decades, further straining health systems, people and communities. It’s often said that cancer is not one, but many diseases. In fact, there are more than 200 forms of cancer, and all of these are caused by cells in the body acquiring the ability to grow and proliferate uncontrollably. Deaths from cancer are usually caused by secondary tumours, which form when cancer […]
CELL DEATH
______________ CELL DEATH: ____________ _ The image shows webbed hand due to apoptosis abnormalities. It is important that inter-digital cell death happens otherwise a webbed limb will develop rather than a five digit limb. _ The image shows paw of a mouse embryo that has been stained with a dye that specifically labels cells that have undergone apoptosis. The apoptotic cells appear as bright green dots between the developing digits. _ As a tadpole changes into a frog, the cells in the tadpole tail are induced to undergo apoptosis; as a consequence, the tail is lost. All the changes that occur during metamorphosis, including the induction of apoptosis in the tail, are stimulated by an increase in thyroid hormone in the blood of a frog. _ The figure shows light micrograph of normal and apoptotic human leukemia cell illustrating chromatin condensation and nuclear fragmentation. _________________________________ _________________________________ Prologue: A vast […]
