Dr Rajiv Desai
An Educational Blog
CELL DEATH
______________ CELL DEATH: ____________ _ The image shows webbed hand due to apoptosis abnormalities. It is important that inter-digital cell death happens otherwise a webbed limb will develop rather than a five digit limb. _ The image shows paw of a mouse embryo that has been stained with a dye that specifically labels cells that have undergone apoptosis. The apoptotic cells appear as bright green dots between the developing digits. _ As a tadpole changes into a frog, the cells in the tadpole tail are induced to undergo apoptosis; as a consequence, the tail is lost. All the changes that occur during metamorphosis, including the induction of apoptosis in the tail, are stimulated by an increase in thyroid hormone in the blood of a frog. _ The figure shows light micrograph of normal and apoptotic human leukemia cell illustrating chromatin condensation and nuclear fragmentation. _________________________________ _________________________________ Prologue: A vast […]
ALLERGY
ALLERGY: ______ ______ Prologue: Medical representatives of pharmaceutical industry frequently visit doctors to promote their products and shower doctors with drug samples, gifts and tours. One medical representative gifted me a perfume to promote his new product. I do not use perfumes. However, human mind is curious and when a perfume was given to me as a gift, I thought why not use it. Two weeks after using perfume, I developed itching skin rash over my body known as ‘Urticaria’ and dermatologist diagnosed it as allergy to perfume. The priciest perfumes and skin care products can cause allergic reactions because of the chemicals that give them their scent. In one fragrance, there may be as many as 26 allergens. The figure above shows urticarial skin rash in another patient. Allergy is not a disease but a mechanism which may play a role in a number of disorders. You can be allergic to anything […]
