Dr Rajiv Desai

An Educational Blog

Novel Approach to Diabetes Mellitus

Novel Approach to Diabetes Mellitus: ________ The figure below shows diabetic patient self-administering insulin injection:   ________ My novel hypothesis on diabetes mellitus (DM): _ Everybody knows that insulin is the only treatment of type 1 diabetes mellitus (T1DM). However in type 2 diabetes mellitus (T2DM) diet, exercise, oral hypoglycemic agents (OHA) precede insulin therapy and only when OHA fails or severe diabetes at onset warrant insulin therapy. There are reports of short term early insulin therapy in all T2DM to protect b-cells of pancreas. I propose a hypothesis that every T2DM patient needs insulin treatment from day one of diagnosis and it ought to be continued indefinitely. By the time diagnosis of diabetes is made, 50 to 80 % of b-cells of pancreas are dead (dysfunctional). The logic is that exogenous insulin will reduce load on surviving b-cells of pancreas, protect surviving b-cells and achieve better glycemic control and […]

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ALLERGY

ALLERGY: ______ ______ Prologue: Medical representatives of pharmaceutical industry frequently visit doctors to promote their products and shower doctors with drug samples, gifts and tours. One medical representative gifted me a perfume to promote his new product. I do not use perfumes. However, human mind is curious and when a perfume was given to me as a gift, I thought why not use it. Two weeks after using perfume, I developed itching skin rash over my body known as ‘Urticaria’ and dermatologist diagnosed it as allergy to perfume. The priciest perfumes and skin care products can cause allergic reactions because of the chemicals that give them their scent. In one fragrance, there may be as many as 26 allergens. The figure above shows urticarial skin rash in another patient. Allergy is not a disease but a mechanism which may play a role in a number of disorders. You can be allergic to anything […]

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